The microRNA-34a-Induced Senescence-Associated Secretory Phenotype (SASP) Favors Vascular Smooth Muscle Cells Calcification

The senescence of vascular smooth muscle cells (VSMCs), characterized by the acquisition of senescence-associated secretory phenotype (SASP), is relevant for VSMCs osteoblastic differentiation and vascular calcification (VC). MicroRNA-34a (miR-34a) is a driver of such phenomena and could play a role...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Zuccolo, Estella, Badi, Ileana, Scavello, Francesco, Gambuzza, Irene, Mancinelli, Luigi, Macrì, Federica, Tedesco, Calogero C., Veglia, Fabrizio, Bonfigli, Anna Rita, Olivieri, Fabiola, Raucci, Angela
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352675/
https://ncbi.nlm.nih.gov/pubmed/32585876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124454
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