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The Connexin 43 Regulator Rotigaptide Reduces Cytokine-Induced Cell Death in Human Islets

Background: Intercellular communication mediated by cationic fluxes through the Connexin family of gap junctions regulates glucose-stimulated insulin secretion and beta cell defense against inflammatory stress. Rotigaptide (RG, ZP123) is a peptide analog that increases intercellular conductance in c...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Ghiasi, Seyed Mojtaba, Hansen, Jakob Bondo, Christensen, Dan Ploug, Tyrberg, Björn, Mandrup-Poulsen, Thomas
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352593/
https://ncbi.nlm.nih.gov/pubmed/32560352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124311
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