Drugs Targeting Tumor-Initiating Cells Prolong Survival in a Post-Surgery, Post-Chemotherapy Ovarian Cancer Relapse Model

Disease recurrence is the major cause of morbidity and mortality of ovarian cancer (OC). In terms of maintenance therapies after platinum-based chemotherapy, PARP inhibitors significantly improve the overall survival of patients with BRCA mutations but is of little benefit to patients without homolo...

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Publicado en:Cancers (Basel)
Autores principales: Harrington, Brittney S., Ozaki, Michelle K., Caminear, Michael W., Hernandez, Lidia F., Jordan, Elizabeth, Kalinowski, Nicholas J., Goldlust, Ian S., Guha, Rajarshi, Ferrer, Marc, Thomas, Craig, Shetty, Jyoti, Tran, Bao, Wong, Nathan, House, Carrie D., Annunziata, Christina M.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352549/
https://ncbi.nlm.nih.gov/pubmed/32575908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061645
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