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Multifactorial Activation of NLRP3 Inflammasome: Relevance for a Precision Approach to Atherosclerotic Cardiovascular Risk and Disease

Chronic low-grade inflammation, through the specific activation of the NACHT leucine-rich repeat- and PYD-containing (NLRP)3 inflammasome-interleukin (IL)-1β pathway, is an important contributor to the development of atherosclerotic cardiovascular disease (ASCVD), being triggered by intracellular ch...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Baragetti, Andrea, Catapano, Alberico Luigi, Magni, Paolo
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352274/
https://ncbi.nlm.nih.gov/pubmed/32585928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124459
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