Therapeutic Efficacy of ABN401, a Highly Potent and Selective MET Inhibitor, Based on Diagnostic Biomarker Test in MET-Addicted Cancer

The receptor tyrosine kinase c-MET regulates processes essential for tissue remodeling and mammalian development. The dysregulation of c-MET signaling plays a role in tumorigenesis. The aberrant activation of c-MET, such as that caused by gene amplification or mutations, is associated with many canc...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Kim, Jooseok, Park, Kyung Eui, Jeong, Yoo-Seong, Kim, YeongMun, Park, Hayeon, Nam, Ji-Hye, Jung, Kyungsoo, Son, Woo Sung, Jung, Hun Soon, Lee, Jong-Hwa, Jeong, Seong Hoon, Kim, Nam Ah, Ha, Jae Du, Cho, Sung Yun, Choi, Yoon-La, Chung, Suk-Jae, Choi, Jun Young, Hong, Sungyoul, Shin, Young Kee
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352216/
https://ncbi.nlm.nih.gov/pubmed/32549194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061575
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