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Compressive Stimulation Enhances Ovarian Cancer Proliferation, Invasion, Chemoresistance, and Mechanotransduction via CDC42 in a 3D Bioreactor

This report investigates the role of compressive stress on ovarian cancer in a 3D custom built bioreactor. Cells within the ovarian tumor microenvironment experience a range of compressive stimuli that contribute to mechanotransduction. As the ovarian tumor expands, cells are exposed to chronic load...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Novak, Caymen M., Horst, Eric N., Lin, Emily, Mehta, Geeta
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352213/
https://ncbi.nlm.nih.gov/pubmed/32532057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061521
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