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Bad Neighborhood: Fibrotic Stroma as a New Player in Melanoma Resistance to Targeted Therapies

Current treatments for metastatic cutaneous melanoma include immunotherapies and drugs targeting key molecules of the mitogen-activated protein kinase (MAPK) pathway, which is often activated by BRAF driver mutations. Overall responses from patients with metastatic BRAF mutant melanoma are better wi...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Diazzi, Serena, Tartare-Deckert, Sophie, Deckert, Marcel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352197/
https://ncbi.nlm.nih.gov/pubmed/32466585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061364
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