Good Cop, Bad Cop: Defining the Roles of Δ40p53 in Cancer and Aging

The tumour suppressor p53 is essential for maintaining DNA integrity, and plays a major role in cellular senescence and aging. Understanding the mechanisms that contribute to p53 dysfunction can uncover novel possibilities for improving cancer therapies and diagnosis, as well as cognitive decline as...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Steffens Reinhardt, Luiza, Zhang, Xiajie, Wawruszak, Anna, Groen, Kira, De Iuliis, Geoffry N., Avery-Kiejda, Kelly A.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352174/
https://ncbi.nlm.nih.gov/pubmed/32585821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061659
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