Associations of nicotidamide-N-methyltransferase, FTO, and IRX3 genetic variants with body mass index and resting energy expenditure in Mexican subjects

The enzyme nicotidamide-N-methyltransferase (NNMT) regulates adipose tissue energy expenditure through increasing nicotinamide adenosine dinucleotide (NAD(+)) content. NNMT methylates nicotinamide to N(1)-methylnicotidamide (MNA-1) using S-adenosyl methionine. The rs694539 NNMT polymorphism is assoc...

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發表在:Sci Rep
Main Authors: Bañales-Luna, Maciel, Figueroa-Vega, Nicté, Marín-Aragón, Carolina Ivet, Perez-Luque, Elva, Ibarra-Reynoso, Lorena, Gallardo-Blanco, Hugo L., López-Aguilar, Itzel, Malacara, Juan Manuel
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351746/
https://ncbi.nlm.nih.gov/pubmed/32651404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67832-7
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