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The serotonin neurotransmitter modulates virulence of enteric pathogens

The gut-brain axis is crucial to microbial-host interactions. The neurotransmitter serotonin is primarily synthesized in the gastrointestinal (GI) tract, where it is secreted into the lumen and subsequently removed by the serotonin transporter, SERT. We show that serotonin decreases virulence gene e...

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Foilsithe in:Cell Host Microbe
Main Authors: Kumar, Aman, Russell, Regan, Pifer, Reed, Menezes-Garcia, Zelia, Cuesta, Santiago, Narayanan, Sanjeev, MacMillan, John B., Sperandio, Vanessa
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351610/
https://ncbi.nlm.nih.gov/pubmed/32521224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.05.004
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