Attenuation of Dupuytren’s fibrosis via targeting of the STAT1 modulated IL-13Rα1 response

Fibrotic disorders represent common complex disease pathologies that are therapeutically challenging. Inflammation is associated with numerous fibrotic pathogeneses; however, its role in the multifaceted mechanisms of fibrosis remains unclear. IL-13 is implicated in aberrant responses involved in fi...

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Veröffentlicht in:Sci Adv
Hauptverfasser: Akbar, Moeed, Garcia-Melchor, Emma, Chilaka, Sabarinadh, Little, Kevin J., Sood, Shatakshi, Reilly, James H., Liew, Foo Y., McInnes, Iain B., Millar, Neal L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for the Advancement of Science 2020
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351483/
https://ncbi.nlm.nih.gov/pubmed/32695877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz8272
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