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Construction and assessment of the immunogenicity and bactericidal activity of fusion protein porin A from Neisseria meningitidis serogroups A and B admixed with OMV adjuvant as a novel vaccine candidate

OBJECTIVE(S): The porins A and B and also outer membrane vesicles (OMVs) of Neisseria meningitidis are used for vaccine purposes. In the present study, we aimed to design a new vaccine candidate based on a fusion of PorA of serogroups A and B of N. meningitidis admixed with OMV and evaluate it in an...

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Detalhes bibliográficos
Publicado no:Iran J Basic Med Sci
Main Authors: Afrough, Parviz, Asadi Karam, Mohammad Reza, Vaziri, Farzam, Behrouzi, Ava, Siadat, Seyed Davar
Formato: Artigo
Idioma:Inglês
Publicado em: Mashhad University of Medical Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351441/
https://ncbi.nlm.nih.gov/pubmed/32695289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2020.40470.9
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