B-Lymphoid Blast Phase of Chronic Myeloid Leukemia: A Case Report and Review of the Literature

Chronic myeloid leukemia (CML) is a clonal hematopoietic stem cell disorder characterized by a reciprocal translocation, t(9;22) (q34.1;q11.2). This leads to fusion of the BCR and ABL1 genes, encoding an active tyrosine kinase that causes unregulated proliferation of the myeloid lineage. The BCR/ABL...

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Pubblicato in:AJSP Rev Rep
Autori principali: Ware, Alisha D., Wake, Laura, Brown, Patrick, Webster, Jonathan A., Smith, B. Douglas, Duffield, Amy S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351361/
https://ncbi.nlm.nih.gov/pubmed/32656356
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