Progress not panacea: vancomycin powder efficacy and dose evaluated in an in vivo mouse model of spine implant infection

BACKGROUND: Intrawound vancomycin powder (VP) has been rapidly adopted in spine surgery with apparent benefit demonstrated in limited, retrospective studies. Randomized trials, basic science, and dose response studies are scarce. PURPOSE: This study aims to test the efficacy and dose effect of VP ov...

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Detalhes bibliográficos
Publicado no:Spine J
Main Authors: Park, Howard Y., Hegde, Vishal, Zoller, Stephen D., Sheppard, William, Hamad, Christopher, Smith, Ryan A., Sprague, Marina M., Proal, Joshua D., Hoang, John, Loftin, Amanda, Blumstein, Gideon, Burke, Zachary, Cevallos, Nicolas, Scaduto, Anthony A., Bernthal, Nicholas M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351246/
https://ncbi.nlm.nih.gov/pubmed/31863932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.spinee.2019.12.007
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