GM-CSF Calibrates Macrophage Defense and Wound Healing Programs during Intestinal Infection and Inflammation

Macrophages play a central role in intestinal immunity, but inappropriate macrophage activation is associated with inflammatory bowel disease (IBD). Here, we identify granulocyte-macrophage colony stimulating factor (GM-CSF) as a critical regulator of intestinal macrophage activation in patients wit...

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Vydáno v:Cell Rep
Hlavní autoři: Castro-Dopico, Tomas, Fleming, Aaron, Dennison, Thomas W., Ferdinand, John R., Harcourt, Katherine, Stewart, Benjamin J., Cader, Zaeem, Tuong, Zewen K., Jing, Chenzhi, Lok, Laurence S.C., Mathews, Rebeccah J., Portet, Anaïs, Kaser, Arthur, Clare, Simon, Clatworthy, Menna R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351110/
https://ncbi.nlm.nih.gov/pubmed/32640223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107857
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