A rapid high-throughput sequencing-based approach for the identification of unknown bacterial pathogens in whole blood

High-throughput DNA sequencing (HTS) of pathogens in whole blood samples is hampered by the high host/pathogen nucleic acids ratio. We describe a novel and rapid bacterial enrichment procedure whose implementation is exemplified in simulated bacteremic human blood samples. The procedure involves dep...

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Detalhes bibliográficos
Publicado no:Future Sci OA
Main Authors: Israeli, Ofir, Makdasi, Efi, Cohen-Gihon, Inbar, Zvi, Anat, Lazar, Shirley, Shifman, Ohad, Levy, Haim, Gur, David, Laskar, Orly, Beth-Din, Adi
Formato: Artigo
Idioma:Inglês
Publicado em: Future Science Ltd 2020
Assuntos:
Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351085/
https://ncbi.nlm.nih.gov/pubmed/32670604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2144/fsoa-2020-0013
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