Chemoradioimmunotherapy of inoperable stage III non-small cell lung cancer: immunological rationale and current clinical trials establishing a novel multimodal strategy

Immune-checkpoint inhibitors (ICI) have dramatically changed the landscape of lung cancer treatment. Preclinical studies investigating combination of ICI with radiation show a synergistic improvement of tumor control probability and have resulted in the development of novel therapeutic strategies. F...

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Vydáno v:Radiat Oncol
Hlavní autoři: Käsmann, Lukas, Eze, Chukwuka, Taugner, Julian, Roengvoraphoj, Olarn, Dantes, Maurice, Schmidt-Hegemann, Nina-Sophie, Schiopu, Sanziana, Belka, Claus, Manapov, Farkhad
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7350600/
https://ncbi.nlm.nih.gov/pubmed/32646443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13014-020-01595-3
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