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Caffeic acid and chlorogenic acid cytotoxicity, genotoxicity and impact on global DNA methylation in human leukemic cell lines

Dietary phenolic compounds such as caffeic and chlorogenic acid exert an antiproliferative effect and modulate the gene-specific DNA methylation status in human breast tumor cells, but it remains unclear whether they interfere with global DNA methylation in human leukemia cells. We examined whether...

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Veröffentlicht in:Genet Mol Biol
Hauptverfasser: Hernandes, Lívia Cristina, Machado, Ana Rita Thomazela, Tuttis, Katiuska, Ribeiro, Diego Luís, Aissa, Alexandre Ferro, Dévoz, Paula Pícoli, Antunes, Lusânia Maria Greggi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Sociedade Brasileira de Genética 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7350414/
https://ncbi.nlm.nih.gov/pubmed/32644097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1678-4685-GMB-2019-0347
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