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Seneca Valley Virus 3C(pro) Cleaves PABPC1 to Promote Viral Replication

Seneca Valley Virus (SVV) is an oncolytic virus of the Picornaviridae family, which has emerged in recent years. The impact of SVV on host cell translation remains unknown. Here, we showed, for the first time, that SVV infection cleaved poly(A) binding protein cytoplasmic 1 (PABPC1). In SVV-infected...

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Detalhes bibliográficos
Publicado no:Pathogens
Main Authors: Xue, Qiao, Liu, Huisheng, Zhu, Zixiang, Xue, Zhaoning, Liu, Xiangtao, Zheng, Haixue
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7350346/
https://ncbi.nlm.nih.gov/pubmed/32512928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens9060443
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