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Overcoming Tumor Resistance to Oncolyticvaccinia Virus with Anti-PD-1-Based Combination Therapy by Inducing Antitumor Immunity in the Tumor Microenvironment

The tumor microenvironment (TME) comprises different types of immune cells, which limit the therapeutic efficacy of most drugs. Although oncolytic virotherapy (OVT) boosts antitumor immunity via enhanced infiltration of tumor-infiltrated lymphocytes (TILs), immune checkpoints on the surface of tumor...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Yoo, So Young, Badrinath, Narayanasamy, Jeong, Su-Nam, Woo, Hyun Young, Heo, Jeong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7350271/
https://ncbi.nlm.nih.gov/pubmed/32575351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8020321
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