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Kappa free light chains is a valid tool in the diagnostics of MS: A large multicenter study

OBJECTIVE: To validate kappa free light chain (KFLC) and lambda free light chain (LFLC) indices as a diagnostic biomarker in multiple sclerosis (MS). METHODS: We performed a multicenter study including 745 patients from 18 centers (219 controls and 526 clinically isolated syndrome (CIS)/MS patients)...

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Veröffentlicht in:Mult Scler
Hauptverfasser: Leurs, CE, Twaalfhoven, HAM, Lissenberg-Witte, BI, van Pesch, V, Dujmovic, I, Drulovic, J, Castellazzi, M, Bellini, T, Pugliatti, M, Kuhle, J, Villar, LM, Alvarez-Cermeño, JC, Alvarez-Lafuente, R, Hegen, H, Deisenhammer, F, Walchhofer, LM, Thouvenot, E, Comabella, M, Montalban, X, Vécsei, L, Rajda, C, Galimberti, D, Scarpini, E, Altintas, A, Rejdak, K, Frederiksen, JL, Pihl-Jensen, G, Jensen, PEH, Khalil, M, Voortman, MM, Fazekas, F, Saiz, A, La Puma, D, Vercammen, M, Vanopdenbosch, L, Uitdehaag, BMJ, Killestein, J, Bridel, C, Teunissen, C
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7350201/
https://ncbi.nlm.nih.gov/pubmed/31066634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1352458519845844
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