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N-Terminal Fatty Acids of NEF(MUT) Are Required for the CD8(+) T-Cell Immunogenicity of In Vivo Engineered Extracellular Vesicles
We recently described a cytotoxic CD8(+) T lymphocyte (CTL) vaccine platform based on the intramuscular (i.m.) injection of DNA eukaryotic vectors expressing antigens of interest fused at the C-terminus of HIV-1 Nef(mut), i.e., a functionally defective mutant that is incorporated at quite high level...
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| Publicat a: | Vaccines (Basel) |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7350016/ https://ncbi.nlm.nih.gov/pubmed/32456079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8020243 |
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