Colorectal Cancer Early Detection in Stool Samples Tracing CpG Islands Methylation Alterations Affecting Gene Expression

Colorectal cancer (CRC) is a major cause of cancer mortality. Early diagnosis is relevant for its prevention and treatment. Since DNA methylation alterations are early events in tumourigenesis and can be detected in cell-free DNA, they represent promising biomarkers for early CRC diagnosis through n...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Vega-Benedetti, Ana Florencia, Loi, Eleonora, Moi, Loredana, Orrù, Sandra, Ziranu, Pina, Pretta, Andrea, Lai, Eleonora, Puzzoni, Marco, Ciccone, Letizia, Casadei-Gardini, Andrea, Cabras, Francesco, Fortunato, Federica, Restivo, Angelo, Zorcolo, Luigi, Scartozzi, Mario, Zavattari, Patrizia
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7349989/
https://ncbi.nlm.nih.gov/pubmed/32599859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124494
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