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Maternal Tryptophan Supplementation Protects Adult Rat Offspring against Hypertension Programmed by Maternal Chronic Kidney Disease: Implication of Tryptophan-Metabolizing Microbiome and Aryl Hydrocarbon Receptor

Hypertension and chronic kidney disease (CKD) can originate during early-life. Tryptophan metabolites generated by different pathways have both detrimental and beneficial effects. In CKD, uremic toxins from the tryptophan-generating metabolites are endogenous ligands of the aryl hydrocarbon receptor...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Hsu, Chien-Ning, Lin, I-Chun, Yu, Hong-Ren, Huang, Li-Tung, Tiao, Mao-Meng, Tain, You-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7349830/
https://ncbi.nlm.nih.gov/pubmed/32604820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124552
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