TERC Variants Associated with Short Leukocyte Telomeres: Implication of Higher Early Life Leukocyte Telomere Attrition as Assessed by the Blood-and-Muscle Model

Short leukocyte telomere length (LTL) is associated with atherosclerotic cardiovascular disease (ASCVD). Mendelian randomisation studies, using single nucleotide polymorphisms (SNPs) associated with short LTL, infer a causal role of LTL in ASCVD. Recent results, using the blood-and-muscle model, ind...

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Pubblicato in:Cells
Autori principali: Toupance, Simon, Stathopoulou, Maria G., Petrelis, Alexandros M., Gorenjak, Vesna, Labat, Carlos, Lai, Tsung-Po, Visvikis-Siest, Sophie, Benetos, Athanase
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
Soggetti:
Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7349705/
https://ncbi.nlm.nih.gov/pubmed/32486379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061360
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