Conditionally Reprogrammed Cells from Patient-Derived Xenograft to Model Neuroendocrine Prostate Cancer Development

Neuroendocrine prostate cancer (NEPC) is a lethal subtype of prostate cancer. It develops mainly via NE transdifferentiation of prostate adenocarcinoma in response to androgen receptor (AR)-inhibition therapy. The study of NEPC development has been hampered by a lack of clinically relevant models. W...

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Bibliographische Detailangaben
Veröffentlicht in:Cells
Hauptverfasser: Ci, Xinpei, Hao, Jun, Dong, Xin, Xue, Hui, Wu, Rebecca, Choi, Stephen Yiu Chuen, Haegert, Anne M., Collins, Colin C., Liu, Xuefeng, Lin, Dong, Wang, Yuzhuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7349646/
https://ncbi.nlm.nih.gov/pubmed/32512818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061398
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