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Evaluation of the CRISPR/Cas9 Genetic Constructs in Efficient Disruption of Porcine Genes for Xenotransplantation Purposes Along with an Assessment of the Off-Target Mutation Formation

The increasing life expectancy of humans has led to an increase in the number of patients with chronic diseases and organ failure. However, the imbalance between the supply and the demand for human organs is a serious problem in modern transplantology. One of many solutions to overcome this problem...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Ryczek, Natalia, Hryhorowicz, Magdalena, Lipiński, Daniel, Zeyland, Joanna, Słomski, Ryszard
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7349392/
https://ncbi.nlm.nih.gov/pubmed/32604937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11060713
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