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IL-6 trans-Signaling Impairs Sprouting Angiogenesis by Inhibiting Migration, Proliferation and Tube Formation of Human Endothelial Cells

Sprouting angiogenesis is the formation of new capillaries from existing vessels in response to tissue hypoxia due to growth/development, repair/healing, and also chronic inflammation. In this study, we aimed to elucidate the effect of IL-6, a pleiotropic cytokine with both pro-inflammatory and anti...

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Bibliografiske detaljer
Udgivet i:Cells
Main Authors: Zegeye, Mulugeta M, Andersson, Blanka, Sirsjö, Allan, Ljungberg, Liza U
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7349366/
https://ncbi.nlm.nih.gov/pubmed/32517159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061414
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