Newcastle Disease Virus (NDV) Oncolytic Activity in Human Glioma Tumors Is Dependent on CDKN2A-Type I IFN Gene Cluster Codeletion

Glioblastoma (GBM) is the most aggressive and frequent primary brain tumor in adults with a median overall survival of 15 months. Tumor recurrence and poor prognosis are related to cancer stem cells (CSCs), which drive resistance to therapies. A common characteristic in GBM is CDKN2A gene loss, loca...

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Publicat a:Cells
Autors principals: García-Romero, Noemi, Palacín-Aliana, Irina, Esteban-Rubio, Susana, Madurga, Rodrigo, Rius-Rocabert, Sergio, Carrión-Navarro, Josefa, Presa, Jesús, Cuadrado-Castano, Sara, Sánchez-Gómez, Pilar, García-Sastre, Adolfo, Nistal-Villan, Estanislao, Ayuso-Sacido, Angel
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7349162/
https://ncbi.nlm.nih.gov/pubmed/32516884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061405
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