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Identification of Prion Disease-Related Somatic Mutations in the Prion Protein Gene (PRNP) in Cancer Patients

Prion diseases are caused by misfolded prion protein (PrP(Sc)) and are accompanied by spongiform vacuolation of brain lesions. Approximately three centuries have passed since prion diseases were first discovered around the world; however, the exact role of certain factors affecting the causative age...

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Published in:Cells
Main Authors: Kim, Yong-Chan, Won, Sae-Young, Jeong, Byung-Hoon
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7349074/
https://ncbi.nlm.nih.gov/pubmed/32560489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061480
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