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Identification of Prion Disease-Related Somatic Mutations in the Prion Protein Gene (PRNP) in Cancer Patients

Prion diseases are caused by misfolded prion protein (PrP(Sc)) and are accompanied by spongiform vacuolation of brain lesions. Approximately three centuries have passed since prion diseases were first discovered around the world; however, the exact role of certain factors affecting the causative age...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Kim, Yong-Chan, Won, Sae-Young, Jeong, Byung-Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7349074/
https://ncbi.nlm.nih.gov/pubmed/32560489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061480
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