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Heterogeneity of Metabolic Vulnerability in Imatinib-Resistant Gastrointestinal Stromal Tumor

Metabolic reprogramming is a hallmark of cancer cells in response to targeted therapy. Decreased glycolytic activity with enhanced mitochondrial respiration secondary to imatinib has been shown in imatinib-sensitive gastrointestional stromal tumors (GIST). However, the role of energy metabolism in i...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Huang, Wen-Kuan, Gao, Jiwei, Chen, Ziqing, Shi, Hao, Yuan, Juan, Cui, Huanhuan L., Yeh, Chun-Nan, Bränström, Robert, Larsson, Catharina, Li, Shuijie, Lui, Weng-Onn
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348861/
https://ncbi.nlm.nih.gov/pubmed/32466502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061333
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