Computational Drug Repositioning for Chagas Disease Using Protein-Ligand Interaction Profiling

Chagas disease, caused by Trypanosoma cruzi (T. cruzi), affects nearly eight million people worldwide. There are currently only limited treatment options, which cause several side effects and have drug resistance. Thus, there is a great need for a novel, improved Chagas treatment. Bifunctional enzym...

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I publikationen:Int J Mol Sci
Huvudupphovsmän: Juárez-Saldivar, Alfredo, Schroeder, Michael, Salentin, Sebastian, Haupt, V. Joachim, Saavedra, Emma, Vázquez, Citlali, Reyes-Espinosa, Francisco, Herrera-Mayorga, Verónica, Villalobos-Rocha, Juan Carlos, García-Pérez, Carlos A., Campillo, Nuria E., Rivera, Gildardo
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348847/
https://ncbi.nlm.nih.gov/pubmed/32560043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124270
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