GINIP, a G(αi)-Interacting Protein, Functions as a Key Modulator of Peripheral GABA(B) Receptor-Mediated Analgesia

One feature of neuropathic pain is a reduced GABAergic inhibitory function. Nociceptors have been suggested to play a key role in this process. However, the mechanisms behind nociceptor-mediated modulation of GABA signaling remain to be elucidated. Here we describe the identification of GINIP, a G(α...

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Publicat a:Neuron
Autors principals: Gaillard, Stéphane, Lo Re, Laure, Mantilleri, Annabelle, Hepp, Régine, Urien, Louise, Malapert, Pascale, Alonso, Serge, Deage, Michael, Kambrun, Charline, Landry, Marc, Low, Sarah A., Alloui, Abdelkrim, Lambolez, Bertrand, Scherrer, Grégory, Le Feuvre, Yves, Bourinet, Emmanuel, Moqrich, Aziz
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348640/
https://ncbi.nlm.nih.gov/pubmed/25242222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.08.056
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