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慢性髓性白血病一种新剪接体ABL(Δexon7+35INS)的发现及其与酪氨酸激酶抑制剂耐药的相关性
OBJECTIVE: To explore whether the ABL(Δexon7) and ABL(35INS) spliceosome contributed to TKIs resistance. METHODS: Screening ABL(Δexon7) and ABL(35INS) in 74 normal people and 76 CML patients (53 patients in remission and 23 patients with TKIs resistance) by using polyacrylamide gel electrophoresis c...
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| Publié dans: | Zhonghua Xue Ye Xue Za Zhi |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Editorial office of Chinese Journal of Hematology
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7348335/ https://ncbi.nlm.nih.gov/pubmed/27431076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3760/cma.j.issn.0253-2727.2016.06.012 |
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