OSBPL2 Is Required for the Binding of COPB1 to ATGL and the Regulation of Lipid Droplet Lipolysis

The accumulation of giant lipid droplets (LDs) increases the risk of metabolic disorders including obesity and insulin resistance. The lipolysis process involves the activation and transfer of lipase, but the molecular mechanism is not completely understood. The translocation of ATGL, a critical lip...

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Bibliografske podrobnosti
izdano v:iScience
Main Authors: Wang, Tianming, Wei, Qinjun, Liang, Lihong, Tang, Xujun, Yao, Jun, Lu, Yajie, Qu, Yuan, Chen, Zhibin, Xing, Guangqian, Cao, Xin
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348002/
https://ncbi.nlm.nih.gov/pubmed/32650117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101252
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