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Nano-imaging trace elements at organelle levels in substantia nigra overexpressing α-synuclein to model Parkinson’s disease

Sub-cellular trace element quantifications of nano-heterogeneities in brain tissues offer unprecedented ways to explore at elemental level the interplay between cellular compartments in neurodegenerative pathologies. We designed a quasi-correlative method for analytical nanoimaging of the substantia...

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Publicat a:Commun Biol
Autors principals: Lemelle, Laurence, Simionovici, Alexandre, Colin, Philippe, Knott, Graham, Bohic, Sylvain, Cloetens, Peter, Schneider, Bernard L.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347932/
https://ncbi.nlm.nih.gov/pubmed/32647232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-1084-0
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