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Induction of a local muscular dystrophy using electroporation in vivo: an easy tool for screening therapeutics

Intramuscular injection and electroporation of naked plasmid DNA (IMEP) has emerged as a potential alternative to viral vector injection for transgene expression into skeletal muscles. In this study, IMEP was used to express the DUX4 gene into mouse tibialis anterior muscle. DUX4 is normally express...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Derenne, Aline, Tassin, Alexandra, Nguyen, Thuy Hang, De Roeck, Estelle, Jenart, Vincianne, Ansseau, Eugénie, Belayew, Alexandra, Coppée, Frédérique, Declèves, Anne-Emilie, Legrand, Alexandre
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347864/
https://ncbi.nlm.nih.gov/pubmed/32647247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68135-7
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