The Transcriptional Network That Controls Growth Arrest and Macrophage Differentiation in the Human Myeloid Leukemia Cell Line THP-1

The response of the human acute myeloid leukemia cell line THP-1 to phorbol esters has been widely studied to test candidate leukemia therapies and as a model of cell cycle arrest and monocyte-macrophage differentiation. Here we have employed Cap Analysis of Gene Expression (CAGE) to analyze a dense...

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Publicat a:Front Cell Dev Biol
Autors principals: Gažová, Iveta, Lefevre, Lucas, Bush, Stephen J., Clohisey, Sara, Arner, Erik, de Hoon, Michiel, Severin, Jessica, van Duin, Lucas, Andersson, Robin, Lengeling, Andreas, Hume, David A., Summers, Kim M.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347797/
https://ncbi.nlm.nih.gov/pubmed/32719792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00498
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