Mimicking the Organic and Inorganic Composition of Anabolic Bone Enhances Human Mesenchymal Stem Cell Osteoinduction and Scaffold Mechanical Properties

Engineered bone graft designs have been largely inspired by adult bone despite functionally significant differences from the composition of anabolic bone in both the mineralized and non-mineralized fractions. Specifically, anabolic bone contains hydroxyapatite with ionic substitutions that facilitat...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Mondragón, Eli, Cowdin, Mitzy, Taraballi, Francesca, Minardi, Silvia, Tasciotti, Ennio, Gregory, Carl A., Kaunas, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Bioengineering and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347795/
https://ncbi.nlm.nih.gov/pubmed/32719790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00753
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