Mimicking the Organic and Inorganic Composition of Anabolic Bone Enhances Human Mesenchymal Stem Cell Osteoinduction and Scaffold Mechanical Properties

Engineered bone graft designs have been largely inspired by adult bone despite functionally significant differences from the composition of anabolic bone in both the mineralized and non-mineralized fractions. Specifically, anabolic bone contains hydroxyapatite with ionic substitutions that facilitat...

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Dettagli Bibliografici
Pubblicato in:Front Bioeng Biotechnol
Autori principali: Mondragón, Eli, Cowdin, Mitzy, Taraballi, Francesca, Minardi, Silvia, Tasciotti, Ennio, Gregory, Carl A., Kaunas, Roland
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Bioengineering and Biotechnology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347795/
https://ncbi.nlm.nih.gov/pubmed/32719790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00753
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