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Prevalence of PD-L1 expression is associated with EMAST, density of peritumoral T-cells and recurrence-free survival in operable non-metastatic colorectal cancer

INTRODUCTION: Microsatellite instability (MSI) predict response to anti-PD1 immunotherapy in colorectal cancer (CRC). CRCs with MSI have higher infiltration of immune cells related to a better survival. Elevated Microsatellite Alterations at Tetranucleotides (EMAST) is a form of MSI but its associat...

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Vydáno v:Cancer Immunol Immunother
Hlavní autoři: Watson, Martin M., Lea, Dordi, Gudlaugsson, Einar, Skaland, Ivar, Hagland, Hanne R., Søreide, Kjetil
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347699/
https://ncbi.nlm.nih.gov/pubmed/32314040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02573-0
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