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Stem cell factor produced by tumor cells expands myeloid-derived suppressor cells in mice

Immunotherapy is a novel treatment approach for cancers; however, its therapeutic effects are impeded by myeloid-derived suppressor cells (MDSCs). This study aimed to determine how MDSCs are expanded in cancer hosts. MDSCs were positive for Gr-1 and CD11b. Hepa1-6 hepatoma cells, EL4 lymphoma cells,...

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Publicat a:Sci Rep
Autors principals: Lee, Wei-Chen, Hsu, Pao-Yueh, Hsu, Hsiu-Ying
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347545/
https://ncbi.nlm.nih.gov/pubmed/32647215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68061-8
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