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dnmt1 function is required to maintain retinal stem cells within the ciliary marginal zone of the zebrafish eye

The ciliary marginal zone (CMZ) of the zebrafish retina contains a population of actively proliferating resident stem cells, which generate retinal neurons throughout life. The maintenance methyltransferase, dnmt1, is expressed within the CMZ. Loss of dnmt1 function results in gene misregulation and...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Angileri, Krista M., Gross, Jeffrey M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347529/
https://ncbi.nlm.nih.gov/pubmed/32647199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68016-z
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