Characterising the prognostic potential of HLA-DR during colorectal cancer development

HLA-DR, an MHC class II molecule that mediates antigen presentation, is a favourable prognostic indicator in colorectal cancer (CRC). However, the dynamics and location of HLA-DR expression during CRC development are unclear. We aimed to define HLA-DR expression by immunohistochemistry in colorectal...

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Veröffentlicht in:Cancer Immunol Immunother
Hauptverfasser: Dunne, Margaret R., Phelan, James J., Michielsen, Adriana J., Maguire, Aoife A., Dunne, Cara, Martin, Petra, Noonan, Sinead, Tosetto, Miriam, Geraghty, Robert, Fennelly, David, Sheahan, Kieran, Ryan, Elizabeth J., O’Sullivan, Jacintha
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347515/
https://ncbi.nlm.nih.gov/pubmed/32306077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02571-2
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