Increased Susceptibility of Mice Lacking Renin-b to Angiotensin II-induced Organ Damage

Several cardiac and renal diseases are attributed to a dysregulation of the renin angiotensin system (RAS). Renin, the rate-limiting enzyme of the RAS, has two isoforms. The classical renin isoform (renin-a) encoding preprorenin is mainly confined to the juxtaglomerular cells and released into the c...

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Vydáno v:Hypertension
Hlavní autoři: Nakagawa, Pablo, Nair, Anand R., Agbor, Larry, Gomez, Javier, Wu, Jing, Zhang, Shao Yang, Lu, Ko-Ting, Morgan, Donald A., Rahmouni, Kamal, Grobe, Justin L., Sigmund, Curt D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347438/
https://ncbi.nlm.nih.gov/pubmed/32507043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.120.14972
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