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Characterization of a long-term mouse primary liver 3D tissue model recapitulating innate-immune responses and drug-induced liver toxicity

Three-dimensional liver in vitro systems have recently attracted a lot of attention in drug development. These systems help to gain unprecedented insights into drug-induced liver injury (DILI), as they more closely reproduce liver biology, and as drug effects can be studied in isolated and controlla...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nudischer, Ramona, Renggli, Kasper, Hierlemann, Andreas, Roth, Adrian B., Bertinetti-Lapatki, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347206/
https://ncbi.nlm.nih.gov/pubmed/32645073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235745
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