MiR-1165-3p Suppresses Th2 Differentiation via Targeting IL-13 and PPM1A in a Mouse Model of Allergic Airway Inflammation

PURPOSE: CD4(+)T cells are essential in the pathogenesis of allergic asthma. We have previously demonstrated that microRNA-1165-3p (miR-1165-3p) was significantly reduced in T-helper type (Th) 2 cells and that miR-1165-3p was a surrogate marker for atopic asthma. Little is known about the mechanisms...

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Detalhes bibliográficos
Publicado no:Allergy Asthma Immunol Res
Main Authors: Wang, Zhengxia, Ji, Ningfei, Chen, Zhongqi, Sun, Zhixiao, Wu, Chaojie, Yu, Wenqing, Hu, Fan, Huang, Mao, Zhang, Mingshun
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7346992/
https://ncbi.nlm.nih.gov/pubmed/32638565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4168/aair.2020.12.5.859
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