ERBB3-induced furin promotes the progression and metastasis of ovarian cancer via the IGF1R/STAT3 signaling axis

High-grade serous carcinoma, accounts for up to 70% of all ovarian cases. Furin, a proprotein convertase, is highly expressed in high-grade serous carcinoma of ovarian cancer patients, and its expression is even higher in tumor omentum than in normal omentum, the preferred site of ovarian cancer met...

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Vydáno v:Oncogene
Hlavní autoři: Chen, Changliang, Gupta, Prachi, Parashar, Deepak, Nair, Gopakumar G, George, Jasmine, Geethadevi, Anjali, Wang, Wei, Tsaih, Shirng-Wern, Bradley, William, Ramchandran, Ramani, Rader, Janet S., Chaluvally-Raghavan, Pradeep, Pradeep, Sunila
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7346970/
https://ncbi.nlm.nih.gov/pubmed/32029900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1194-7
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