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Allosteric influence of extremophile hairpin motif mutations on the protein splicing activity of a hyperthermophilic intein

Protein splicing is a post-translational process mediated by an intein, whereby the intein excises itself from a precursor protein with concomitant ligation of the flanking two polypeptides. The intein that interrupts the DNA Polymerase II in the extreme hyperthermophile Pyrococcus abyssi has a β-ha...

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Bibliografiske detaljer
Udgivet i:Biochemistry
Main Authors: Chiarolanzio, Kathryn C., Pusztay, Jennifer M., Chavez, Angel, Zhao, Jing, Xie, Jian, Wang, Chunyu, Mills, Kenneth V.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7346874/
https://ncbi.nlm.nih.gov/pubmed/32559373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00348
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