Inflammescent CX3CR1(+)CD57(+)CD8(+) T cells are generated and expanded by IL-15

HIV infection is associated with an increase in the proportion of activated CD8(+) memory T cells (Tmem) that express CX3CR1, but how these cells are generated and maintained in vivo is unclear. We demonstrate that increased CX3CR1 expression on CD8(+) Tmem in people living with HIV (PLWH) is depend...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Morris, Stephen R., Chen, Bonnie, Mudd, Joseph C., Panigrahi, Soumya, Shive, Carey L., Sieg, Scott F., Cameron, Cheryl M., Zidar, David A., Funderburg, Nicholas T., Younes, Souheil-Antoine, Rodriguez, Benigno, Gianella, Sara, Lederman, Michael M., Freeman, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7346586/
https://ncbi.nlm.nih.gov/pubmed/32369455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.132963
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