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Ursolic acid reverses liver fibrosis by inhibiting interactive NOX4/ROS and RhoA/ROCK1 signalling pathways

Liver fibrosis is the reversible deposition of extracellular matrix (ECM) and scar formation after liver damage by various stimuli. The interaction between NOX4/ROS and RhoA/ROCK1 in liver fibrosis is not yet clear. Ursolic acid (UA) is a traditional Chinese medicine with anti-fibrotic effects, but...

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Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Wan, Sizhe, Luo, Fangyun, Huang, Chenkai, Liu, Cong, Luo, Qingtian, Zhu, Xuan
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7346053/
https://ncbi.nlm.nih.gov/pubmed/32496208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103282
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